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These polysaccharides promote M2 macrophage polarization, characterized by increased IL-10 production, while concurrently suppressing Th17 activation and IL-17 production ( Figure 2 illustrates how herbal polysaccharides leverage SCFA production to coordinate these anti-inflammatory mechanisms

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GSH is present and synthesized in the cytosol of all mammalian cells by a two-step regulated process (see Figure 1) [42]